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At the time of the explosion five years ago, the nanites entered the atmosphere and spread across the globe.
Nanites exist within almost every living being, including plants and have bonded to their molecular structure in Rex's Universe on Earth. Normally, nanites are completely harmless; however, when activated, they mutate the biology of their host, giving them grotesque physical features and/or special abilities. These are called EVOs which stands for Exponentially Variegated Organisms.
They appeared in the Ben 10/Generator Rex: Heroes United special.
- Ben 10/Generator Rex: Heroes United (first appearance)
- White Knight is the only living being that is free of nanites in Rex's world.
- Though a Galvanic Mechamorph's body is made up of billions of small cell-like creatures called nanites,[pop-up 1] they are not related to the ones seen in Rex's Universe.[DR 1]